nProtect is, to my understanding, a sort of "off the self" program game makers buy and install into their game builds (it's also a rootkit that logs your key presses, so when gaming, dedicate yourself only to the game and don't access any sensitive info on your PC). Of course, there may be a level of customization for game makers to use, but for the most part, the bulk of the program cannot be edited by the game makers. So anything big from nProtect should come from the program maker themselves. Any other specific edits per game, though, I assume those are under the game maker's control.
As I said before, nothing beats human intervention in these cases, and it is why it's important to have GMs on site, since bots may not be constantly human operated, but the humans behind them are always looking for better ways to deploy them and keep them running. It's, like with malware, a race between companies against those seeking to self profit off them, and off us.