Yesterday, I had to re-install PSO2 NA via Tweaker because when I ran the game (before I had to start using the Tweaker), I got some message saying that "The game will not be updated."
So I activated Developer Mode, used the Windows Store fix, and fixed permissions/GameGuard/EXE's, but the game crashes before it gets to the title screen.
This also happens when I try to start the game without using the Tweaker.