In the story the ARKS leader Luther starts going off the rails. Leading into his plans getting foiled time and time again.
After said foiling of plans he goes insane and starts calling himself Loser because all he does is lose, going so far as starting to go by that name. While one name of one antagonist is quite the minor thing for some reason it annoys me to see "Luther" instead of "Loser" when i fight the boss.