It is not an issue on my end, but a friend's end. Lately he has been trying to run PSO2:NGS. He has been able to get to the launcher, but after it closes the game refuses to boot up and show a window. The game says it is already running, and is still considered a background process in his task manager.
One time the loading image and the anti-cheat pop-up appeared, afterwards there was still nothing. Even after an hour of waiting for it to boot up.